Cerium dioxide - Exposure

Cerium dioxide is used in various applications, e.g. fuel cells, wood preservatives, varnish or abrasives and polishing agents.
There are actually no studies on general hazard, thus no epidemiological data are available.

 

Real occurring concentrations of cerium dioxide nanoparticles (CeO2) in the environment are not yet known. But as an alternative, the expected environmental cerium dioxide concentrations (PEC value) can be predicted using specific computer models.

Depending on the cell type cerium dioxide nanoparticles induce different biological responses in vitro. Only a small number of studies demonstrate a toxic effect of these nanoparticles, in many cases the cerium dioxide nanoparticles protect the cells by scavenging oxygen radicals in the cells.

Studies in rodents demonstrated that cerium dioxide nanoparticles can be taken up by the animals dependent on the exposure route. There they can induce inflammation but also may act as a radical scavenger and protect the body.

 

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