Copper (Cu) and copper oxide (CuO) particles can be taken up by different types of cells.


Inside a cell the nanoparticles were accumulated in vesicular- or lysosomal-like structures.Uncoated particles will dissolve over the time in these organelles and induce either hot spots of high concentrations of Cu ions or may create hot spots of reactive oxygen species (ROS) formation [1,2].


Literature arrow down

  1. Studer, AM et al. (2010), Toxicol Lett, 197(3): 169-174.
  2. Hanagata, N et al. (2011), ACS Nano, 5(12): 9326-9338.


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