Only very high doses of strontium carbonate (SrCO3) can stress the cells and cause them to die off.

 

In vitro experiments from the project NanoCare  with two differently modified, well-characterised variants of strontium carbonate that were applied to human lung cells have shown that only high doses of at least 25 µg/cm2 of the hydrophobic particles can cause stress in cells and a decrease in the cell vitality after 72 hours. No effects were caused by the hydrophilic variant with particles of almost identical primary particle size. No negative effects on the cells were observed during studies with ten different cell lines of different origins treated with up to 10 µg particles/cm2 [1].

Using the so-called vector model which displays some of the elementary cell effects [2], partners of the NanoCare project proved that SrCO3 has little or no effects at all. Excessive, overloading concentrations of at least 120 µg particles per 106 phagocytes were observed to damage the cell function and lead to the formation of reactive oxygen species (ROS).

 

Literature arrow down

  1. NanoCare 2009, Final Scientific Report, ISBN 978-3-89746-108-6. (PDF-Document, 19 MB).
  2. Bruch, J et al. (2004), Int J Hyg Environ Health, 207(3): 203-216.

 

 

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