Since zinx oxide (ZnO) nanoparticles occur in cosmetic products, textiles or plastics as bound particles, it is rather improbable that they are taken up via the lung. Instead, inhalation may occur during particle production and processing.

 

First animal model studies show that inhalation of ZnO nanoparticles may effect a relatively strong but temporary inflammation of the lung [1,2] which resembles the so-called metal fume fever, an influenza-type disease characterized by inflammation of the respiratory tract due to inhalation of metal fumes (mainly zinc fumes) during welding.

 

Literature arrow down

  1. Sayes, CM et al. (2007), Toxicol Sci, 97(1): 163-180.
  2. Warheit, DB et al. (2009), Environ Sci Technol, 43(20): 7939-7945.

 

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