Measuring particle size distribution of nanoparticle enabled medicinal products

The JRC, in close collaboration with researchers from the French CEA, Swiss EMPA, US NCI-NCL and Irish Trinity College, has developed a common strategy for measuring the particle size distribution of nanomedicines. A quick preliminary step to assess sample integrity and stability by low resolution techniques is followed by the combination of complementary high resolution sizing measurements performed both in simple buffers and in complex biological media.

Read more in the erspective review artcile (open access):

F. Caputo et al.: Measuring particle size distribution of nanoparticle enabled medicinal products, the joint view of EUNCL and NCI-NCL. A step by step approach combining orthogonal measurements with increasing complexity, Journal of Controlled Release 299 (2019) 31-43

DOI: 10.1016/j.jconrel.2019.02.030