The German Federal Ministry of Education and Research is funding projects on new, advanced and application-safe materials / nanomaterials as well as measures for risk identification and risk minimisation.
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The German Government’s Action Plan Nanotechnology 2020  provided an integrated concept for detecting the risks of nanomaterials for humans and the environment and for designing sustainable innovations.

This action plan focused on the further development of testing and measurement methods for risk characterisation, the support of research institutions and companies in the application-safe and environmentally compatible design of material innovations, the derivation of options for action for risk management and the further optimisation of risk communication.

This was supported by various higher federal authorities through a joint research strategy entitled “Nanomaterials and other innovative materials: application-safe and environmentally compatible”. The research projects were completed in 2023.

 Early Awareness and Action System for Advanced Materials (Early4AdMa)
Spotlight Research

November 2023: Early Awareness and Action System for Advanced Materials (Early4AdMa)


Hier treffen sich die Partner der Projekte der BMBF Fördermaßnahme NanoCare4.0 Read more


2019-2023 NanoCare4.0 - Reliable material innovations - the new BMBF funding measure

At present, the development and production of new materials are facing fundamental changes. New ways of material development include virtual material development with a computer-aided design, increasingly use digital data for modelling and simulation and support research into new material classes. Safety aspects must therefore be taken into account at an early stage in the development process and throughout the entire life cycle of the material. In order to meet these demands of industry and consumers, the new NanoCare4.0 funding measure is to investigate not only nanomaterials, but all innovative materials that are suspected of having harmful effects on the environment or health.

DaNa 4.0

DaNa4.0 - Data on new, innovative and safe application related materials
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NanoINHAL - In-vitro test methods for airborne nanomaterials to investigate toxic potential and uptake after inhalation exposure using innovative organ-on-a-chip technology
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InnoMat.Life - Innovative Materials and new production processes: Safety along the Life Cycle and in industrial value chains
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CarboBreak - Prerequisites and mechanisms for the release of alveolar fibrous carbon fibre fragments
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MetalSafety - Development of evaluation concepts for fibrous and granular metal compounds - bioavailability, toxicological efficacy profiles and comparative in vitro, ex vivo and in vivo studies
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NanoCELL - Comprehensive characterization and human toxicological assessment of nanocellulose along its life cycle for reliable risk assessment and safe use in environmentally friendly packaging materials
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NanoBioQuant - Quantification of nanomaterials in tissue for regulatory analysis and development of in vitro methods
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CarbonFibreCycle - Carbon fibres in circular economy – release behaviour and toxicity due to thermal and mechanical treatment
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2014-2018: NanoCare 2

The funding initiative “NanoCare" as part of the framework program "From Material to Innovation" anchored in the new High-Tech Strategy aimed at innovation and growth of the industry in Germany. Based on the results and experiences of the previous action “NanoCare & NanoNature” (see below), the topic of safe handling of synthetic nanomaterials - research on the effects on humans and the environment was investigated in several project activities. A close cooperation between companies and research institutions in the university and non-university sector, the involvement of contributions from small and medium-sized enterprises (SMEs) and the exploitation of project results in Germany was of outstanding importance. From 2014-2018, a total of 11 projects was funded.


CaNTser - Investigating the toxic potential of carbon nanotubes after long-term inhalation
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NanoBEL – Biological Elimination of Complex Diagnostic Nanoparticles
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ProCycle - Analysis and toxicological evaluation of dusts from recycling and recycling processes of nanocomposites and strategies for risk minimisation
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nanoGRAVUR : nanostructured materials – grouping for occupational health, consumer and environmental protection and risk mitigation
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nanoCOLT - Long-term effect of modified carbon black nanoparticles on healthy and damaged lungs
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DENANA - Design criteria for sustainable nanomaterials
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NanoUmwelt - Risk analysis of engineered nanomaterials in the environment: identification, quantification and analysis of the human- and ecotoxicological effects
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InhalT-90: 90 days inhalation testing with CeO2 in the rat and subsequent analysis of gene expression profiles for the early detection of toxic / carcinogenic effects
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NANOSUPPE - Behaviour of engineered nanoparticles in the pathway wastewater - sewage sludge - plant using the examples TiO2, CeO2, MWCNT and quantum dots
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NANOMOBIL : Synthetic Silver Nanoparticles in the system Soil-Groundwater - mobility, effects on cohabitation and interaction between hydro-, pedo- and biosphere
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NanoBioDetect - Nanoparticles in the tissue: detection, quantification and presentation of biological effect markers
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DaNa 2.0

DaNa 2.0 - Data and knowledge on Nanomaterials - Processing of socially relevant scientific facts
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2013 – 2019 ERA-Net SIINN – Safe Implementation of Innovative Nanoscience and Nanotechnology

FP7 ERA-NET SIINN - Safe Implementation of Innovative Nanoscience and Nanotechnology The ERA-NET SIINN Safe Implementation of Innovative Nanoscience and Nanotechnology promotes the safe and rapid transfer of European research results in nanoscience and nanotechnology (N&N) into industrial applications. National and regional resources will be virtually pooled to create a transnational programme of research. SIINN will bring together today's fragmented research activities on the potential risks of engineered nanomaterials for environment, human health, and safety.


NANOHETER - HETERoaggregation of manufactured NANOparticles with naturally occurring colloids in surface waters
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NANOGECO - Nanoparticle generation by atomization processes in spray coating
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Nano Safe Leather - The effect on human health of silver-titanium dioxide nanomaterials -treated leathers for footwear industry
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NANOaers - Fate of aerosolized nanoparticles: the influence of surface active substances on lung deposition and respiratory effects
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NanoWIR2ES - NanoWire Intelligent Re-design and Recycling for Environmental Safety
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CERASAFE – Safe production and use of nanomaterials in the ceramic industry
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NanoFARM - Fate and Effects of agriculturally relevant Nanomaterials
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FATENANO - translocation, biological fate, stability and effective dose of engineered nanomaterials (ENM) for Nanosafety Studies
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NANO-Transfer - Transfer of carbon based nanomaterials (C-MNMs) into the aquatic environment: fate, effects, bioaccumulation, food web transfer, contaminant transport and use in the remediation of polluted waters
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ICONS - Integrated Testing Strategy for mechanistic assessment of the respiratory toxicity of functionalized multiwalled carbon nanotubes (MWCNT)
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PLATOX -In vitro and in vivo investigations to generate validated toxicity data of graphene nanoplatelets vs a carbon black reference
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NanoToxClass - Establishing nanomaterial grouping / classification strategies according to toxicity and biological effects for supporting risk assessment
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FENOMENO - Fate and effect of wastewater-born manufactured nanomaterials in aquatic ecosystems
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nanOxiMet - Oxidant generating capacity as a metric to allow grouping of nanomaterials and prediction of human health effects
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nanoIndEx - Assessment of Individual Exposure to manufactured nanomaterials by means of personal monitors and samplers
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2009-2014: NanoNature

NanoNature aimed at strengthening potential nanomaterial market segments in the environmental field and at enhancing the export of environmentally relevant materials and technologies. In addition, systematic analyses were carried out and adapted measuring methods have been developed to assess the release, distribution, fate, and effect of synthetic nanoparticles and nanomaterials in the environment.


kitNano-SCR - Development of nanoscale SCR catalysts for combined NOx and soot reduction in diesel engines
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NanoMembrane - Nanoporous ceramic membranes for use in sustainable closed-cycle water- and solvent-saving methods
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NanoKiesel - Nanoscale silica slurry - Technology developments on nanoscale silica slurry use in mineral building materials with the aim of improving material properties
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UMSICHT - Assessment of the environmental hazards of silver nanomaterials: From chemical particles to technical products
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NAPASAN - Nanoparticles for groundwater damage repair
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NanoTRACK - Nanoparticle life cycle studies based on [45Ti]TiO2 and [105Ag] Ag0
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NanoPurification - Development of advanced materials and methods for water and sewage treatment by means of functional nanocomposites
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NanoPHARM - New photocatalytically active composite materials for elimination of pharmaceutical residues
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NADINE - Nanomodified diamond electrodes for inline disinfection in different fields of application
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Fe-NANOSIT - Iron-based nanoparticles and nanocomposite structures for removal of contaminantsfrom groundwater and sewage
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NANOFLOW  - Mobility of synthetic nanoparticles in water-saturated and variably water-saturated subsoils
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NanoSAN - A nanotechnological clean up method – In situ use of iron oxide nanoparticles for elimination of harmful substances from abandoned polluted areas
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2009-2014 NanoCare

NanoCare intended to further investigate systematically the human-toxicological effects and interactions occurring during the production, processing, and application of synthetic nanomaterials. External and internal exposures have been be quantified, material-specific toxicity parameters were determined, and mechanisms of action were identified to detect and predict possible toxic effects on humans along the life cycle of the investigated nanomaterials.


Nanosilver particles - Mechanisms of action and investigation of their possible interaction with tissues, cells and molecules. Definition of their relevant potential for intolerance
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NanoMED - Toxicological characterisation of nanomaterials for the diagnostic imaging in medicine
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NanoExpo - Nanobalance detectors for individual-related measure-ments of nanoparticle exposures
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DaNa - Acquisition, evaluation and public-oriented presentation of society-relevant data and findings relating to nanomaterials
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CarboTox - Development of screening methods to analyse cancerogenous potential of carbon nano tubes
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nanoGEM - Nanostructured Materials - health, exposure and material properties
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NanoKON - Systematic evaluation of health effects of nanoscale contrast agents
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CarbonBlack - Prediction of the human-toxicological effect of synthetic carbon black nanoparticles
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2008-2014: Inno.CNT - Innovation Alliance Carbon Nanotubes

In a scientific alliance with more than 90 renowned partners from research and industry, the Inno.CNT initiative is systematically advancing the development of carbon nanotubes (CNT). The tiny carbon nanotubes have the potential to open up brand-new dimensions in materials technology and bring a unique quality to numerous products and applications.

Inno.CNT – CarboLifeCycle

CarboLifeCycle - Innovation Alliance Carbon Nanotubes: Innovation for industry and society
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Inno.CNT – CarboAir

CarboAir - Innovation Alliance Carbon Nanotubes: Innovation for industry and society
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Inno.CNT – CarboSafe

CarboSafe - Innovation Alliance Carbon Nanotubes: Innovation for industry and society
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2006-2009: NanoCare-Cluster: NanoCare; INOS; Tracer


TRACER -Toxicology and Health Risk Assessment of Carbon Nanomaterials
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A German Initiative on the Health Aspects of Synthetic Nanoparticles:
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INOS - Identification and Assessment of the Effects of Engineered NanOparticleS on Human and Environmental Health
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