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Spotlight December 2022: Fighting tumors with micro robots
When we, the DaNa team as operators of the website nanopartikel.info, write about nanobots, i.e. nanometre-sized machines, we point out that these machines belong to science fiction, may even remain a utopia – i.e. never realisable. On the significantly larger micro-scale, however, small machines are conceivable that could help in the therapy of diseases, e.g. cancer. Such an approach is now presented by S. Schürle from ETH Zurich, who is developing magnetically controllable microrobots. She is using naturally occurring bacteria that have a magnetic “core” and with the help of which they can be steered to the target as microrobots.
This approach is not entirely new in terms of the basic idea, but it is significantly improved by the Zurich working group because rotating magnetic fields are used to make the bacteria rotate. The impression is that the microrobots now work like micro-drilling machines and drill their way non-destructively between cells to get from blood vessels through the blood vessel wall to tumour cells. You can read about the results she has achieved and the new approaches S. Schürle is exploring on the ETH Zurich website and in the original publication cited there (Gwisai T, Mirkhani N, Christiansen MG, Nguyen TT, Ling V, Schuerle S: Magnetic torque-driven living microrobots for increased tumour infiltration, Science Robotics 26 October 2022, doi: https://doi.org/10.1126/scirobotics.abo0665)
Weitere Spotlights
Spotlight May 2022: Nano-ghosts” – Risk assessment of submicron-sized particles in food biased towards fictional “nano”
The European Commission has issued a ban on the colorant titanium dioxide in food. Titanium dioxide, which provides a nice shine and bright white color, can potentially damage genetic material. We chose a review article from 2022 for the May 2022 Spotlight that addresses the risk assessment of food-grade titanium dioxide (E171) and the resulting […]
Read moreSpotlight October 2022: The titanium dioxide debate – why the current ECHA and EFSA hazard classification should be questioned
Due to various reports and scientific studies, titanium dioxide (TiO2)was also banned in Europe this year (2022) for use as a food additive with the indication that it could possibly be carcinogenic to humans. Although no case of tumour induction in humans has been reported since the use of this material in micro but also […]
Read moreSpotlight February 2022: Probabilistic risk assessment – the keystone for the future of toxicology
The basics of toxicology are constantly being reconsidered, and the approach to risk assessment is therefore constantly being put to the test, because, as William Osler is cited in this publication, “Medicine (toxicology) is a science of uncertainty and an art of probability“. In this recent paper, the team around Thomas Hartung (Johns-Hopkins University/University of […]
Read moreSpotlight April 2021: Nanomaterials and Fake News – a commentary based on an example
In February 2021, the article “The invisible killer lurking in our consumer products” appeared, describing nanoparticles as a greater danger than Corona [1]. “The use of nanomaterials” would be “unregulated” and “nanomaterials are so small that they cannot be determined once they are part of a product”. So what is the truth of these statements? […]
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