Spotlight December 2022: Fighting tumors with micro robots

When we, the DaNa team as operators of the website nanopartikel.info, write about nanobots, i.e. nanometre-sized machines, we point out that these machines belong to science fiction, may even remain a utopia – i.e. never realisable. On the significantly larger micro-scale, however, small machines are conceivable that could help in the therapy of diseases, e.g. cancer. Such an approach is now presented by S. Schürle from ETH Zurich, who is developing magnetically controllable microrobots. She is using naturally occurring bacteria that have a magnetic “core” and with the help of which they can be steered to the target as microrobots.
This approach is not entirely new in terms of the basic idea, but it is significantly improved by the Zurich working group because rotating magnetic fields are used to make the bacteria rotate. The impression is that the microrobots now work like micro-drilling machines and drill their way non-destructively between cells to get from blood vessels through the blood vessel wall to tumour cells. You can read about the results she has achieved and the new approaches S. Schürle is exploring on the ETH Zurich website and in the original publication cited there (Gwisai T, Mirkhani N, Christiansen MG, Nguyen TT, Ling V, Schuerle S: Magnetic torque-driven living microrobots for increased tumour infiltration, Science Robotics 26 October 2022, doi: https://doi.org/10.1126/scirobotics.abo0665)