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Spotlight December 2022: Fighting tumors with micro robots
When we, the DaNa team as operators of the website nanopartikel.info, write about nanobots, i.e. nanometre-sized machines, we point out that these machines belong to science fiction, may even remain a utopia – i.e. never realisable. On the significantly larger micro-scale, however, small machines are conceivable that could help in the therapy of diseases, e.g. cancer. Such an approach is now presented by S. Schürle from ETH Zurich, who is developing magnetically controllable microrobots. She is using naturally occurring bacteria that have a magnetic “core” and with the help of which they can be steered to the target as microrobots.
This approach is not entirely new in terms of the basic idea, but it is significantly improved by the Zurich working group because rotating magnetic fields are used to make the bacteria rotate. The impression is that the microrobots now work like micro-drilling machines and drill their way non-destructively between cells to get from blood vessels through the blood vessel wall to tumour cells. You can read about the results she has achieved and the new approaches S. Schürle is exploring on the ETH Zurich website and in the original publication cited there (Gwisai T, Mirkhani N, Christiansen MG, Nguyen TT, Ling V, Schuerle S: Magnetic torque-driven living microrobots for increased tumour infiltration, Science Robotics 26 October 2022, doi: https://doi.org/10.1126/scirobotics.abo0665)
Weitere Spotlights
Spotlight August 2021: Towards FAIR nanosafety data
In August we would like to present a paper on FAIR data. The paper published in Nature Nanotechnology in June 2021 summarises the challenges and provides recommendations for the efficient reuse of nanosafety data in line with the recently established FAIR guiding principles: findable, accessible, interoperable and reusable. This article summarises the know-how on the […]
Read moreSpotlight January 2021: Nanoplastics challenge – How to improve tracking of nanopolystyrene distribution in the environment.
In January, we present a paper published in the Nature Journal communications materials. The article focuses on the development of a new detection method of nanopolystyrene. The method not only makes it possible to detect nanoplastics in the environment for the first time, but also to determine their accumulation in plants and animals. Nanoplastics, which […]
Read moreSpotlight October 2022: The titanium dioxide debate – why the current ECHA and EFSA hazard classification should be questioned
Due to various reports and scientific studies, titanium dioxide (TiO2)was also banned in Europe this year (2022) for use as a food additive with the indication that it could possibly be carcinogenic to humans. Although no case of tumour induction in humans has been reported since the use of this material in micro but also […]
Read moreSpotlight February 2022: Probabilistic risk assessment – the keystone for the future of toxicology
The basics of toxicology are constantly being reconsidered, and the approach to risk assessment is therefore constantly being put to the test, because, as William Osler is cited in this publication, “Medicine (toxicology) is a science of uncertainty and an art of probability“. In this recent paper, the team around Thomas Hartung (Johns-Hopkins University/University of […]
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