>
Spotlight September: A methodology for the automatic evaluation of data quality and completeness of nanomaterials for risk assessment purposes
This paper describes a method for automatically assessing the quality and completeness of nanosafety data for the purpose of risk assessment. Steps to develop the methodology for assessing data completeness and the methodology for assessing quality are presented. The methodology is tailored to physicochemical and hazard (meta) data, but can also be configured with appropriate criteria to support modeling or exposure assessment. It is based on assessing the quality and completeness of the data contained in the eNanoMapper database using the harmonized data reporting templates introduced in the NANoREG project and further developed in the GRACIOUS project. Combined with expert knowledge, this methodology can be used as a powerful data analysis tool in different contexts. To enable the practical application of the proposed methodology, it has been implemented as an online R-tool (https://shinyapps.greendecision.eu/app/gracious-data-quality) that can be connected to both databases and risk assessment software tools.
Original publication:
Gianpietro Basei, Hubert Rauscher, Nina Jeliazkova & Danail Hristozov (2022). A methodology for the automatic evaluation of data quality and completeness of nanomaterials for risk assessment purposes. Nanotoxicology, 16:2, 195-216, DOI: 10.1080/17435390.2022.2065222
Weitere Spotlights
Spotlight February 2022: Probabilistic risk assessment – the keystone for the future of toxicology
The basics of toxicology are constantly being reconsidered, and the approach to risk assessment is therefore constantly being put to the test, because, as William Osler is cited in this publication, “Medicine (toxicology) is a science of uncertainty and an art of probability“. In this recent paper, the team around Thomas Hartung (Johns-Hopkins University/University of […]
Read moreSpotlight April 2021: Nanomaterials and Fake News – a commentary based on an example
In February 2021, the article “The invisible killer lurking in our consumer products” appeared, describing nanoparticles as a greater danger than Corona [1]. “The use of nanomaterials” would be “unregulated” and “nanomaterials are so small that they cannot be determined once they are part of a product”. So what is the truth of these statements? […]
Read moreSpotlight January 2023: Special issue on Methods and Protocols in Nanotoxicology published
In the first Spotlight of the new year, we present a special issue on methods and protocols in nanotoxicology published in the journal Frontiers in Toxicology. There are still too few harmonized protocols accepted by the scientific community. To improve this situation, project activities are started and special issues of journals like this one are […]
Read moreSpotlight December 2021: Silica nanoparticles improve plant disease resistance
The resistance of plants to various pathogens is often increased in agriculture with various chemicals (“fertilizers”). A new direction is being taken with the use of nanoparticles. These can be sprayed on the plants. In the present study, the model plant Arabidopsis was used to investigate whether silicon dioxide nanoparticles (SiO2) can increase resistance to […]
Read more


