Spotlight August 2020: The nanoGRAVUR Grouping approach

Home > Spotlight August 2020: The nanoGRAVUR Grouping approach

In August, we would like to present a paper of the German BMBF project nanoGRAVUR. nanoGRAVUR dealt from 2015-2018 with the grouping of nanostructured materials with regard to occupational safety, consumer and environmental protection and risk mitigation. The approach is now described by the project partners in this paper.

Due to the variety of synthetic nanomaterials and the numerous modifications (differences in size, shape, chemical composition and surface functionalization), the effort required to investigate effects and behaviour within the framework of regulatory requirements is enormous. Given the variability of possible effects, it is almost impossible to examine the potential risk for each nanomaterial on a case-by-case basis. Grouping or analogy now aims to allow a reliable prediction of hazards from nanomaterials of a group without additional testing by identifying certain properties or parameters.

For each of the three different areas of occupational, consumer and environmental safety, different groups may emerge, but they are based on a harmonised set of material properties with specific analytical methods, descriptors and areas. Proof of concept is provided in this publication by quantitative data on 34 case studies.

 

Original Publication:

Wohlleben, W, Hellack, B, Nickel, C, Herrchen, M, Hund-Rinke, K, Kettler, K, Riebeling, C, Haase, A, Funk, B, Kühnel, D, Göhler, D, Stintz, M, Schumacher, C, Wiemann, M, Keller, J, Landsiedel, R, Broßell, D, Pitzko, S, Kuhlbusch,T (2019), The nanoGRAVUR framework to group (nano)materials for their occupational, consumer, environmental risks based on a harmonized set of material properties, applied to 34 case studies. DOI 10.1039/c9nr03306h

Spotlight August 2020: The nanoGRAVUR Grouping approach

Weitere Spotlights


Spotlight June 2021: Endotoxin – the reason for false-positive toxicity testing for advanced materials? 

Spotlight June 2021: Endotoxin – the reason for false-positive toxicity testing for advanced materials? 

Advanced materials, but also nanomaterials are closely examined to determine whether they trigger biological effects that could be harmful to humans and the environment before they are used in products. This also includes such materials as titanium dioxide, which has been used in a wide variety of products for more than 50 years. A particularly […]

Read more

Spotlight July 2022: New definition on nanomaterials published

Spotlight July 2022: New definition on nanomaterials published

The European Union has published a new definition for nanomaterials as of June 2022. It is recommended that this be used as a basis for future legislation. The new documents can be found on the EC website. In the new “nanodefinition”, the essential components such as the origin or the size range of the particles […]

Read more

Spotlight December 2021: Silica nanoparticles improve plant disease resistance

Spotlight December 2021: Silica nanoparticles improve plant disease resistance

The resistance of plants to various pathogens is often increased in agriculture with various chemicals (“fertilizers”). A new direction is being taken with the use of nanoparticles. These can be sprayed on the plants. In the present study, the model plant Arabidopsis was used to investigate whether silicon dioxide nanoparticles (SiO2) can increase resistance to […]

Read more

Spotlight February 2022: Probabilistic risk assessment – the keystone for the future of toxicology

Spotlight February 2022: Probabilistic risk assessment – the keystone for the future of toxicology

The basics of toxicology are constantly being reconsidered, and the approach to risk assessment is therefore constantly being put to the test, because, as William Osler is cited in this publication, “Medicine (toxicology) is a science of uncertainty and an art of probability“. In this recent paper, the team around Thomas Hartung (Johns-Hopkins University/University of […]

Read more

Skip to content