>
Spotlight May 2022: Nano-ghosts” – Risk assessment of submicron-sized particles in food biased towards fictional “nano”
The European Commission has issued a ban on the colorant titanium dioxide in food. Titanium dioxide, which provides a nice shine and bright white color, can potentially damage genetic material.
We chose a review article from 2022 for the May 2022 Spotlight that addresses the risk assessment of food-grade titanium dioxide (E171) and the resulting potential bias against nanoscale titanium dioxide.
The authors are not interested in avoiding a ban on the use of E171 in food. Rather, it is important that the same bias against a fictitious “nano” hazard be avoided in the future.
The E171 case illustrates how the risk assessment of manufactured particulate food additives is potentially biased toward a supposed nanoscale particle hazard.
The authors summarize that, for example, subacute studies show that oral exposure to E171 does not cause toxicity in rodents or that chronic toxicity studies show that oral exposure to E171 does not cause carcinogenicity or other long-term adverse effects in rodents, even when tested at high doses.
The objective of this review is to reassess the literature on the toxicity of titanium dioxide particles, focusing on studies that are directly relevant to the evaluation of E171.
Original Publication:
Naegeli, H. and C. Gsell (2022). „“Nano-ghosts“: Risk assessment of submicron-sized particles in food biased towards fictional „nano“. EXCLI J 21: 279-299.
Weitere Spotlights
Spotlight April 2022: A new risk assessment of nanomaterials in 3D printing is needed
The use of nanomaterials in 3D printing has great potential. Due to the properties of nanoscale materials, many requirements can be implemented in 3D printing. However, these unique properties based on the size of the particles also lead to the need for new risk assessments. This is because if the nanoparticles are released in the […]
Read moreSpotlight October 2022: The titanium dioxide debate – why the current ECHA and EFSA hazard classification should be questioned
Due to various reports and scientific studies, titanium dioxide (TiO2)was also banned in Europe this year (2022) for use as a food additive with the indication that it could possibly be carcinogenic to humans. Although no case of tumour induction in humans has been reported since the use of this material in micro but also […]
Read moreSpotlight October 2020: Nanosafety – Topic of the Future
Research on nanosafety is a driver of innovation as the spotlight in July has demonstrated. But furthermore, this research field is built on routine as well if researchers look for the “needle in the haystack”. In many areas the safety research initiates the development of new methods, e.g. for the determination of nanoparticles within exposed organisms via […]
Read moreSpotlight August 2022: Three-stage model for the formation of micro- and nanoplastic particles.
Plastic pollution is a global problem that will continue to affect humanity for more than 100 years. There is the visible pollution, e.g. plastic debris in the environment, which leads to death for many animals (because they mistakenly think the plastic is food and eat it or because they get caught in the plastic waste). […]
Read more