>
Spotlight May 2022: Nano-ghosts” – Risk assessment of submicron-sized particles in food biased towards fictional “nano”
The European Commission has issued a ban on the colorant titanium dioxide in food. Titanium dioxide, which provides a nice shine and bright white color, can potentially damage genetic material.
We chose a review article from 2022 for the May 2022 Spotlight that addresses the risk assessment of food-grade titanium dioxide (E171) and the resulting potential bias against nanoscale titanium dioxide.
The authors are not interested in avoiding a ban on the use of E171 in food. Rather, it is important that the same bias against a fictitious “nano” hazard be avoided in the future.
The E171 case illustrates how the risk assessment of manufactured particulate food additives is potentially biased toward a supposed nanoscale particle hazard.
The authors summarize that, for example, subacute studies show that oral exposure to E171 does not cause toxicity in rodents or that chronic toxicity studies show that oral exposure to E171 does not cause carcinogenicity or other long-term adverse effects in rodents, even when tested at high doses.
The objective of this review is to reassess the literature on the toxicity of titanium dioxide particles, focusing on studies that are directly relevant to the evaluation of E171.
Original Publication:
Naegeli, H. and C. Gsell (2022). „“Nano-ghosts“: Risk assessment of submicron-sized particles in food biased towards fictional „nano“. EXCLI J 21: 279-299.
Weitere Spotlights
Spotlight November 2020: Nanotechnology in the public perception
In November, we would like to draw your attention to a publication that examines public perception of the safety of nanomaterials in Austria.It shows, that although there is generally a rather positive attitude towards nanomaterials, there are different opinions on safety issues from different social groups. Further clarification seems necessary. Despite the widespread use of […]
Read moreSpotlight August 2021: Towards FAIR nanosafety data
In August we would like to present a paper on FAIR data. The paper published in Nature Nanotechnology in June 2021 summarises the challenges and provides recommendations for the efficient reuse of nanosafety data in line with the recently established FAIR guiding principles: findable, accessible, interoperable and reusable. This article summarises the know-how on the […]
Read moreSpotlight August 2022: Three-stage model for the formation of micro- and nanoplastic particles.
Plastic pollution is a global problem that will continue to affect humanity for more than 100 years. There is the visible pollution, e.g. plastic debris in the environment, which leads to death for many animals (because they mistakenly think the plastic is food and eat it or because they get caught in the plastic waste). […]
Read moreSpotlight November 2023: Early Awareness and Action System for Advanced Materials (Early4AdMa)
Advanced materials hold immense potential to address global challenges such as environmental degradation, transformation of the energy sector, and development towards circularity. To harness their benefits while ensuring safety and sustainability, regulatory bodies, scientific communities, and industries have recognized the need for proactive approaches. The “Early4AdMa” system is a pre-regulatory risk governance tool for advanced […]
Read more