>
Spotlight May 2022: Nano-ghosts” – Risk assessment of submicron-sized particles in food biased towards fictional “nano”
The European Commission has issued a ban on the colorant titanium dioxide in food. Titanium dioxide, which provides a nice shine and bright white color, can potentially damage genetic material.
We chose a review article from 2022 for the May 2022 Spotlight that addresses the risk assessment of food-grade titanium dioxide (E171) and the resulting potential bias against nanoscale titanium dioxide.
The authors are not interested in avoiding a ban on the use of E171 in food. Rather, it is important that the same bias against a fictitious “nano” hazard be avoided in the future.
The E171 case illustrates how the risk assessment of manufactured particulate food additives is potentially biased toward a supposed nanoscale particle hazard.
The authors summarize that, for example, subacute studies show that oral exposure to E171 does not cause toxicity in rodents or that chronic toxicity studies show that oral exposure to E171 does not cause carcinogenicity or other long-term adverse effects in rodents, even when tested at high doses.
The objective of this review is to reassess the literature on the toxicity of titanium dioxide particles, focusing on studies that are directly relevant to the evaluation of E171.
Original Publication:
Naegeli, H. and C. Gsell (2022). „“Nano-ghosts“: Risk assessment of submicron-sized particles in food biased towards fictional „nano“. EXCLI J 21: 279-299.
Weitere Spotlights
Spotlight July 2022: New definition on nanomaterials published
The European Union has published a new definition for nanomaterials as of June 2022. It is recommended that this be used as a basis for future legislation. The new documents can be found on the EC website. In the new “nanodefinition”, the essential components such as the origin or the size range of the particles […]
Read moreSpotlight April 2022: A new risk assessment of nanomaterials in 3D printing is needed
The use of nanomaterials in 3D printing has great potential. Due to the properties of nanoscale materials, many requirements can be implemented in 3D printing. However, these unique properties based on the size of the particles also lead to the need for new risk assessments. This is because if the nanoparticles are released in the […]
Read moreSpotlight October 2021: Nanopesticides – a proposal for a risk assessment framework
The application of so-called “nanopesticides” (see also cross-sectional text Nanomaterials in plant protection products) is said to have two basic advantages: a smaller amount of pesticide is needed for the same agricultural area and the efficacy is improved. This is necessary to grow enough food for a still growing world population. However, this could also […]
Read moreSpotlight September: A methodology for the automatic evaluation of data quality and completeness of nanomaterials for risk assessment purposes
This paper describes a method for automatically assessing the quality and completeness of nanosafety data for the purpose of risk assessment. Steps to develop the methodology for assessing data completeness and the methodology for assessing quality are presented. The methodology is tailored to physicochemical and hazard (meta) data, but can also be configured with appropriate […]
Read more