>
Spotlight May 2022: Nano-ghosts” – Risk assessment of submicron-sized particles in food biased towards fictional “nano”
The European Commission has issued a ban on the colorant titanium dioxide in food. Titanium dioxide, which provides a nice shine and bright white color, can potentially damage genetic material.
We chose a review article from 2022 for the May 2022 Spotlight that addresses the risk assessment of food-grade titanium dioxide (E171) and the resulting potential bias against nanoscale titanium dioxide.
The authors are not interested in avoiding a ban on the use of E171 in food. Rather, it is important that the same bias against a fictitious “nano” hazard be avoided in the future.
The E171 case illustrates how the risk assessment of manufactured particulate food additives is potentially biased toward a supposed nanoscale particle hazard.
The authors summarize that, for example, subacute studies show that oral exposure to E171 does not cause toxicity in rodents or that chronic toxicity studies show that oral exposure to E171 does not cause carcinogenicity or other long-term adverse effects in rodents, even when tested at high doses.
The objective of this review is to reassess the literature on the toxicity of titanium dioxide particles, focusing on studies that are directly relevant to the evaluation of E171.
Original Publication:
Naegeli, H. and C. Gsell (2022). „“Nano-ghosts“: Risk assessment of submicron-sized particles in food biased towards fictional „nano“. EXCLI J 21: 279-299.
Weitere Spotlights
Spotlight December 2022: Fighting tumors with micro robots
When we, the DaNa team as operators of the website nanopartikel.info, write about nanobots, i.e. nanometre-sized machines, we point out that these machines belong to science fiction, may even remain a utopia – i.e. never realisable. On the significantly larger micro-scale, however, small machines are conceivable that could help in the therapy of diseases, e.g. […]
Read moreSpotlight September: A methodology for the automatic evaluation of data quality and completeness of nanomaterials for risk assessment purposes
This paper describes a method for automatically assessing the quality and completeness of nanosafety data for the purpose of risk assessment. Steps to develop the methodology for assessing data completeness and the methodology for assessing quality are presented. The methodology is tailored to physicochemical and hazard (meta) data, but can also be configured with appropriate […]
Read moreSpotlight October 2023: Improved hydrogen production through novel catalyst made of three metals
Hydrogen is one of the important energy carriers of the future when it comes to climate-relevant energy supply. For example, surplus electricity from wind turbines or solar plants can be converted into hydrogen, allowing the otherwise unused energy to be stored for longer periods. This hydrogen can be used to power trucks and buses for […]
Read moreSpotlight Juli 2020: “Nanosafety – More than just regulatory processes”
Nanosafety is more than just a compulsory aspect of nanomaterials research and regulation. This research area also has great potential to drive new innovations. It is exactly this perspective that is addressed in the special issue “Rethinking Nanosafety: Harnessing Progress and Driving Innovation” by Chen et al. 2020. The article illustrates that especially in the field of […]
Read more