>
Spotlight May 2022: Nano-ghosts” – Risk assessment of submicron-sized particles in food biased towards fictional “nano”
The European Commission has issued a ban on the colorant titanium dioxide in food. Titanium dioxide, which provides a nice shine and bright white color, can potentially damage genetic material.
We chose a review article from 2022 for the May 2022 Spotlight that addresses the risk assessment of food-grade titanium dioxide (E171) and the resulting potential bias against nanoscale titanium dioxide.
The authors are not interested in avoiding a ban on the use of E171 in food. Rather, it is important that the same bias against a fictitious “nano” hazard be avoided in the future.
The E171 case illustrates how the risk assessment of manufactured particulate food additives is potentially biased toward a supposed nanoscale particle hazard.
The authors summarize that, for example, subacute studies show that oral exposure to E171 does not cause toxicity in rodents or that chronic toxicity studies show that oral exposure to E171 does not cause carcinogenicity or other long-term adverse effects in rodents, even when tested at high doses.
The objective of this review is to reassess the literature on the toxicity of titanium dioxide particles, focusing on studies that are directly relevant to the evaluation of E171.
Original Publication:
Naegeli, H. and C. Gsell (2022). „“Nano-ghosts“: Risk assessment of submicron-sized particles in food biased towards fictional „nano“. EXCLI J 21: 279-299.
Weitere Spotlights
Spotlight November 2022: Photonics in nature and bioinspired designs
Science has always taken nature as a model and imitated it. If you look at the field of photonics, i.e. the use of optical technologies for information processing, transmission or storage, the colorful examples in the animal and plant world are perfect basic drawers for technical applications. While colors in nature are used either for […]
Read moreSpotlight November 2023: Early Awareness and Action System for Advanced Materials (Early4AdMa)
Advanced materials hold immense potential to address global challenges such as environmental degradation, transformation of the energy sector, and development towards circularity. To harness their benefits while ensuring safety and sustainability, regulatory bodies, scientific communities, and industries have recognized the need for proactive approaches. The “Early4AdMa” system is a pre-regulatory risk governance tool for advanced […]
Read moreSpotlight December 2021: Silica nanoparticles improve plant disease resistance
The resistance of plants to various pathogens is often increased in agriculture with various chemicals (“fertilizers”). A new direction is being taken with the use of nanoparticles. These can be sprayed on the plants. In the present study, the model plant Arabidopsis was used to investigate whether silicon dioxide nanoparticles (SiO2) can increase resistance to […]
Read moreSpotlight Juli 2020: “Nanosafety – More than just regulatory processes”
Nanosafety is more than just a compulsory aspect of nanomaterials research and regulation. This research area also has great potential to drive new innovations. It is exactly this perspective that is addressed in the special issue “Rethinking Nanosafety: Harnessing Progress and Driving Innovation” by Chen et al. 2020. The article illustrates that especially in the field of […]
Read more