>
Spotlight May 2022: Nano-ghosts” – Risk assessment of submicron-sized particles in food biased towards fictional “nano”
The European Commission has issued a ban on the colorant titanium dioxide in food. Titanium dioxide, which provides a nice shine and bright white color, can potentially damage genetic material.
We chose a review article from 2022 for the May 2022 Spotlight that addresses the risk assessment of food-grade titanium dioxide (E171) and the resulting potential bias against nanoscale titanium dioxide.
The authors are not interested in avoiding a ban on the use of E171 in food. Rather, it is important that the same bias against a fictitious “nano” hazard be avoided in the future.
The E171 case illustrates how the risk assessment of manufactured particulate food additives is potentially biased toward a supposed nanoscale particle hazard.
The authors summarize that, for example, subacute studies show that oral exposure to E171 does not cause toxicity in rodents or that chronic toxicity studies show that oral exposure to E171 does not cause carcinogenicity or other long-term adverse effects in rodents, even when tested at high doses.
The objective of this review is to reassess the literature on the toxicity of titanium dioxide particles, focusing on studies that are directly relevant to the evaluation of E171.
Original Publication:
Naegeli, H. and C. Gsell (2022). „“Nano-ghosts“: Risk assessment of submicron-sized particles in food biased towards fictional „nano“. EXCLI J 21: 279-299.
Weitere Spotlights
Spotlight June 2022: From small to clever – What does the future hold for the safety and sustainability of advanced materials?
The smallest particles in materials research, nanoparticles, have occupied us intensively for more than 20 years to elucidate and further investigate their safety for humans and the environment. Now, however, the development is going from “small = nano” to “clever = advanced”, as discussed in a contribution by international scientists. Thereby, it is a great […]
Read moreSpotlight December 2020: Rethinking Nanosafety – Part II
In December we would like to draw attention to the special issue: Rethinking Nanosafety – Part II in small. In the July Spotlight we already presented Part I. This special issue “Rethinking Nanosafety – Part II” also features research papers by renowned scientists in the field of nanosafety research. The first part of this special […]
Read moreSpotlight February 2021: Nanoobjects in the COVID-vaccine – scientifically correct?
The COVID-19 pandemic induces very different reactions of people on the internet (https://www.cdc.gov/mmwr/volumes/70/wr/mm7002e1.htm) and in the social networks. Without following the conspiracy theories as “5G nanochip hidden in COVID vaccines” some news as “COVID vaccines induce allergic reactions” should be scientifically recognised. The picture from the 5G-nanochip whose plan goes viral on the internet is […]
Read moreSpotlight August 2021: Towards FAIR nanosafety data
In August we would like to present a paper on FAIR data. The paper published in Nature Nanotechnology in June 2021 summarises the challenges and provides recommendations for the efficient reuse of nanosafety data in line with the recently established FAIR guiding principles: findable, accessible, interoperable and reusable. This article summarises the know-how on the […]
Read more