>
Spotlight May 2022: Nano-ghosts” – Risk assessment of submicron-sized particles in food biased towards fictional “nano”
The European Commission has issued a ban on the colorant titanium dioxide in food. Titanium dioxide, which provides a nice shine and bright white color, can potentially damage genetic material.
We chose a review article from 2022 for the May 2022 Spotlight that addresses the risk assessment of food-grade titanium dioxide (E171) and the resulting potential bias against nanoscale titanium dioxide.
The authors are not interested in avoiding a ban on the use of E171 in food. Rather, it is important that the same bias against a fictitious “nano” hazard be avoided in the future.
The E171 case illustrates how the risk assessment of manufactured particulate food additives is potentially biased toward a supposed nanoscale particle hazard.
The authors summarize that, for example, subacute studies show that oral exposure to E171 does not cause toxicity in rodents or that chronic toxicity studies show that oral exposure to E171 does not cause carcinogenicity or other long-term adverse effects in rodents, even when tested at high doses.
The objective of this review is to reassess the literature on the toxicity of titanium dioxide particles, focusing on studies that are directly relevant to the evaluation of E171.
Original Publication:
Naegeli, H. and C. Gsell (2022). „“Nano-ghosts“: Risk assessment of submicron-sized particles in food biased towards fictional „nano“. EXCLI J 21: 279-299.
Weitere Spotlights
Spotlight August 2020: The nanoGRAVUR Grouping approach
In August, we would like to present a paper of the German BMBF project nanoGRAVUR. nanoGRAVUR dealt from 2015-2018 with the grouping of nanostructured materials with regard to occupational safety, consumer and environmental protection and risk mitigation. The approach is now described by the project partners in this paper.Due to the variety of synthetic nanomaterials and the numerous modifications (differences in size, shape, chemical composition and surface functionalization), the effort required to investigate effects and behaviour within the framework of regulatory requirements is…
Read moreSpotlight February 2021: Nanoobjects in the COVID-vaccine – scientifically correct?
The COVID-19 pandemic induces very different reactions of people on the internet (https://www.cdc.gov/mmwr/volumes/70/wr/mm7002e1.htm) and in the social networks. Without following the conspiracy theories as “5G nanochip hidden in COVID vaccines” some news as “COVID vaccines induce allergic reactions” should be scientifically recognised. The picture from the 5G-nanochip whose plan goes viral on the internet is […]
Read moreSpotlight January 2023: Special issue on Methods and Protocols in Nanotoxicology published
In the first Spotlight of the new year, we present a special issue on methods and protocols in nanotoxicology published in the journal Frontiers in Toxicology. There are still too few harmonized protocols accepted by the scientific community. To improve this situation, project activities are started and special issues of journals like this one are […]
Read moreSpotlight April 2022: A new risk assessment of nanomaterials in 3D printing is needed
The use of nanomaterials in 3D printing has great potential. Due to the properties of nanoscale materials, many requirements can be implemented in 3D printing. However, these unique properties based on the size of the particles also lead to the need for new risk assessments. This is because if the nanoparticles are released in the […]
Read more