>
Spotlight May 2022: Nano-ghosts” – Risk assessment of submicron-sized particles in food biased towards fictional “nano”
The European Commission has issued a ban on the colorant titanium dioxide in food. Titanium dioxide, which provides a nice shine and bright white color, can potentially damage genetic material.
We chose a review article from 2022 for the May 2022 Spotlight that addresses the risk assessment of food-grade titanium dioxide (E171) and the resulting potential bias against nanoscale titanium dioxide.
The authors are not interested in avoiding a ban on the use of E171 in food. Rather, it is important that the same bias against a fictitious “nano” hazard be avoided in the future.
The E171 case illustrates how the risk assessment of manufactured particulate food additives is potentially biased toward a supposed nanoscale particle hazard.
The authors summarize that, for example, subacute studies show that oral exposure to E171 does not cause toxicity in rodents or that chronic toxicity studies show that oral exposure to E171 does not cause carcinogenicity or other long-term adverse effects in rodents, even when tested at high doses.
The objective of this review is to reassess the literature on the toxicity of titanium dioxide particles, focusing on studies that are directly relevant to the evaluation of E171.
Original Publication:
Naegeli, H. and C. Gsell (2022). „“Nano-ghosts“: Risk assessment of submicron-sized particles in food biased towards fictional „nano“. EXCLI J 21: 279-299.
Weitere Spotlights
Spotlight October 2023: Improved hydrogen production through novel catalyst made of three metals
Hydrogen is one of the important energy carriers of the future when it comes to climate-relevant energy supply. For example, surplus electricity from wind turbines or solar plants can be converted into hydrogen, allowing the otherwise unused energy to be stored for longer periods. This hydrogen can be used to power trucks and buses for […]
Read moreSpotlight January 2023: Special issue on Methods and Protocols in Nanotoxicology published
In the first Spotlight of the new year, we present a special issue on methods and protocols in nanotoxicology published in the journal Frontiers in Toxicology. There are still too few harmonized protocols accepted by the scientific community. To improve this situation, project activities are started and special issues of journals like this one are […]
Read moreSpotlight June 2021: Endotoxin – the reason for false-positive toxicity testing for advanced materials?
Advanced materials, but also nanomaterials are closely examined to determine whether they trigger biological effects that could be harmful to humans and the environment before they are used in products. This also includes such materials as titanium dioxide, which has been used in a wide variety of products for more than 50 years. A particularly […]
Read moreSpotlight May 2023: Dual energy – edible batteries
An Italian research group reports on edible batteries that supply electric current and can be digested as food, thus providing energy a second time. What sounds funny at first has a serious background, because in medicine, power sources are needed that could be transported through the digestive tract and possibly remain in the body unintentionally, […]
Read more