>
Spotlight May 2022: Nano-ghosts” – Risk assessment of submicron-sized particles in food biased towards fictional “nano”
The European Commission has issued a ban on the colorant titanium dioxide in food. Titanium dioxide, which provides a nice shine and bright white color, can potentially damage genetic material.
We chose a review article from 2022 for the May 2022 Spotlight that addresses the risk assessment of food-grade titanium dioxide (E171) and the resulting potential bias against nanoscale titanium dioxide.
The authors are not interested in avoiding a ban on the use of E171 in food. Rather, it is important that the same bias against a fictitious “nano” hazard be avoided in the future.
The E171 case illustrates how the risk assessment of manufactured particulate food additives is potentially biased toward a supposed nanoscale particle hazard.
The authors summarize that, for example, subacute studies show that oral exposure to E171 does not cause toxicity in rodents or that chronic toxicity studies show that oral exposure to E171 does not cause carcinogenicity or other long-term adverse effects in rodents, even when tested at high doses.
The objective of this review is to reassess the literature on the toxicity of titanium dioxide particles, focusing on studies that are directly relevant to the evaluation of E171.
Original Publication:
Naegeli, H. and C. Gsell (2022). „“Nano-ghosts“: Risk assessment of submicron-sized particles in food biased towards fictional „nano“. EXCLI J 21: 279-299.
Weitere Spotlights
Spotlight February 2022: Probabilistic risk assessment – the keystone for the future of toxicology
The basics of toxicology are constantly being reconsidered, and the approach to risk assessment is therefore constantly being put to the test, because, as William Osler is cited in this publication, “Medicine (toxicology) is a science of uncertainty and an art of probability“. In this recent paper, the team around Thomas Hartung (Johns-Hopkins University/University of […]
Read moreSpotlight November 2022: Photonics in nature and bioinspired designs
Science has always taken nature as a model and imitated it. If you look at the field of photonics, i.e. the use of optical technologies for information processing, transmission or storage, the colorful examples in the animal and plant world are perfect basic drawers for technical applications. While colors in nature are used either for […]
Read moreSpotlight April 2021: Nanomaterials and Fake News – a commentary based on an example
In February 2021, the article “The invisible killer lurking in our consumer products” appeared, describing nanoparticles as a greater danger than Corona [1]. “The use of nanomaterials” would be “unregulated” and “nanomaterials are so small that they cannot be determined once they are part of a product”. So what is the truth of these statements? […]
Read moreSpotlight December 2020: Rethinking Nanosafety – Part II
In December we would like to draw attention to the special issue: Rethinking Nanosafety – Part II in small. In the July Spotlight we already presented Part I. This special issue “Rethinking Nanosafety – Part II” also features research papers by renowned scientists in the field of nanosafety research. The first part of this special […]
Read more