>
Spotlight September: A methodology for the automatic evaluation of data quality and completeness of nanomaterials for risk assessment purposes
This paper describes a method for automatically assessing the quality and completeness of nanosafety data for the purpose of risk assessment. Steps to develop the methodology for assessing data completeness and the methodology for assessing quality are presented. The methodology is tailored to physicochemical and hazard (meta) data, but can also be configured with appropriate criteria to support modeling or exposure assessment. It is based on assessing the quality and completeness of the data contained in the eNanoMapper database using the harmonized data reporting templates introduced in the NANoREG project and further developed in the GRACIOUS project. Combined with expert knowledge, this methodology can be used as a powerful data analysis tool in different contexts. To enable the practical application of the proposed methodology, it has been implemented as an online R-tool (https://shinyapps.greendecision.eu/app/gracious-data-quality) that can be connected to both databases and risk assessment software tools.
Original publication:
Gianpietro Basei, Hubert Rauscher, Nina Jeliazkova & Danail Hristozov (2022). A methodology for the automatic evaluation of data quality and completeness of nanomaterials for risk assessment purposes. Nanotoxicology, 16:2, 195-216, DOI: 10.1080/17435390.2022.2065222
Weitere Spotlights
Spotlight Juli 2020: “Nanosafety – More than just regulatory processes”
Nanosafety is more than just a compulsory aspect of nanomaterials research and regulation. This research area also has great potential to drive new innovations. It is exactly this perspective that is addressed in the special issue “Rethinking Nanosafety: Harnessing Progress and Driving Innovation” by Chen et al. 2020. The article illustrates that especially in the field of […]
Read moreSpotlight October 2022: The titanium dioxide debate – why the current ECHA and EFSA hazard classification should be questioned
Due to various reports and scientific studies, titanium dioxide (TiO2)was also banned in Europe this year (2022) for use as a food additive with the indication that it could possibly be carcinogenic to humans. Although no case of tumour induction in humans has been reported since the use of this material in micro but also […]
Read moreSpotlight February 2022: Probabilistic risk assessment – the keystone for the future of toxicology
The basics of toxicology are constantly being reconsidered, and the approach to risk assessment is therefore constantly being put to the test, because, as William Osler is cited in this publication, “Medicine (toxicology) is a science of uncertainty and an art of probability“. In this recent paper, the team around Thomas Hartung (Johns-Hopkins University/University of […]
Read moreSpotlight September 2023: Fishing for raw materials with proteins
The so-called rare earth elements such as neodymium, dysprosium or cerium are elements that are of great importance for the energy transition; among others they serve as components of magnets in generators for electric power generation, act as luminescent materials in energy-saving lamps or as part of the car exhaust catalytic converter. The global production […]
Read more