>
Spotlight March 2022: Safe Materials from Scratch – Safe-by-Design-Concept in action
In recent decades, German research on nanomaterials and new, innovative materials has been widely expanded by material safety aspects. European initiatives also pay significant attention to this: both the European Union (EU) Green Deal, and the Chemicals Strategy for Sustainability (CSS) aim to create a sustainable, climate-neutral economy with sustainable and safe chemicals and products, while better protecting human health and the environment. The focus is on fostering innovation while addressing global challenges.
The Safe-by-Design (SbD) strategy for nanomaterials and innovative materials is one approach to address precisely these challenges (see also Spotlight Research of November 2021). Risks to humans and the environment should ideally be identified, assessed, and reduced on an early stage of the development process. The European Horizon 2020 project NanoRegII also deals with safe-by-design and is the first project that has now conducted a practical test of the safe-by-design concept. The NanoRegII safe-by-design strategy was implemented at six companies. The experience gained was then evaluated and guidelines for practical implementation of the safe-by-design strategy for the future were developed. In addition to being informative, the guidelines also contain several tools that are intended to help identify risks at an early stage. This should enable an assessment at each step in the innovation process as to whether the innovation should be continued and, if so, which safe-by-design measures need to be further applied to reduce uncertainties. The guidelines thus offer a first approach that can be adapted by each company to its specific requirements for innovation.
Original Publication:
Sánchez Jiménez, A. et al 2022 Safe(r) by design guidelines for the nanotechnology industry. NanoImpact 25, 100385.
Weitere Spotlights
Spotlight August 2020: The nanoGRAVUR Grouping approach
In August, we would like to present a paper of the German BMBF project nanoGRAVUR. nanoGRAVUR dealt from 2015-2018 with the grouping of nanostructured materials with regard to occupational safety, consumer and environmental protection and risk mitigation. The approach is now described by the project partners in this paper.Due to the variety of synthetic nanomaterials and the numerous modifications (differences in size, shape, chemical composition and surface functionalization), the effort required to investigate effects and behaviour within the framework of regulatory requirements is…
Read moreSpotlight April 2021: Nanomaterials and Fake News – a commentary based on an example
In February 2021, the article “The invisible killer lurking in our consumer products” appeared, describing nanoparticles as a greater danger than Corona [1]. “The use of nanomaterials” would be “unregulated” and “nanomaterials are so small that they cannot be determined once they are part of a product”. So what is the truth of these statements? […]
Read moreSpotlight May 2022: Nano-ghosts” – Risk assessment of submicron-sized particles in food biased towards fictional “nano”
The European Commission has issued a ban on the colorant titanium dioxide in food. Titanium dioxide, which provides a nice shine and bright white color, can potentially damage genetic material. We chose a review article from 2022 for the May 2022 Spotlight that addresses the risk assessment of food-grade titanium dioxide (E171) and the resulting […]
Read moreSpotlight June 2021: Endotoxin – the reason for false-positive toxicity testing for advanced materials?
Advanced materials, but also nanomaterials are closely examined to determine whether they trigger biological effects that could be harmful to humans and the environment before they are used in products. This also includes such materials as titanium dioxide, which has been used in a wide variety of products for more than 50 years. A particularly […]
Read more


