Publications

On this page you can find publications resulting from the NanoKon that deals with the topic of Systematic evaluation of health effects of nanoscale contrast agents.

The full text of some publications is copyright protected and can be made available for a certain fee only.

 
Publications in Scientific Journals

Publications in Scientific Journals

2014

  • Tenzer, S., D. Docter, J. Kuharev, A. Musyanovych, V. Fetz, R. Hecht, F. Schlenk, D. Fischer, K. Kiouptsi, C. Reinhardt, K. Landfester, H. Schild, M. Maskos, S. K. Knauer, R. H. Stauber (2013). Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology. Nature Nanotechnology 8(10): 772-781.

  • Pollok S., Ginter T., Gunzel K., Pieper J., Henke A., Stauber R.H., Reichardt W., Kramer O.H. (2013). Interferon alpha-armed nanoparticles trigger rapid and sustained STAT1-dependent anti-viral cellular responses. Cell Signal, 25(4): 989-998.

  • Diesel B., Hoppstadter J., Hachenthal N., Zarbock R., Cavelius C., Wahl B., Thewes N., Jacobs K., Kraegeloh A., Kiemer A.K. (2013). Activation of Rac1 GTPase by nanoparticulate structures in human macrophages. Eur J Pharm Biopharm, 84(2): 315-324.

  • Helou M., Reisbeck M., Tedde S.F., Richter L., Bar L., Bosch J.J., Stauber R.H., Quandt E., Hayden O. (2013). Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation. Lab Chip, 13(6): 1035-1038.

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    2012

    • Gebauer J.S., Malissek M., Simon S., Knauer S.K., Maskos M., Stauber R.H., Peukert W., Treuel L. (2012). Impact of the nanoparticle-protein corona on colloidal stability and protein structure. Langmuir, 28(25): 9673-9679.

     

    2011

    • Tenzer, S., D. Docter, S. Rosfa, A. Wlodarski, J. Kuharev, A. Rekik, S. K. Knauer, C. Bantz, T. Nawroth, C. Bier, J. Sirirattanapan, W. Mann, L. Treuel, R. Zellner, M. Maskos, H. Schild, R. H. Stauber (2011). Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: a comprehensive quantitative proteomic analysis. ACS Nano 5(9): 7155-7167.

     

     
    Contributions to Conferences

    Contributions to Conferences

    2014

    • Astanina K. (2014). Iron oxide nanoparticles impair endothelial integrity: risk for the blood brain barrier? Global Environmental Contamination – Challenges for the Well-Being of the Human Brain, 8.September 2014, Luxembourg. [Oral]

    • Kiemer, A.K. (2014). Nanoparticulate structures amplify inflammantory reactions in macrophages. Global Environmental Contamination – Challenges for the Well-Being of the Human Brain, 8.September 2014, Luxembourg. [Oral]

    • Müller S.G. (2014). In vivo Analyse der Nanopartikel Endothelzell-Interaktion an einem Kolitismodell der Maus. 22. Jahrestagung der Saarländischen Chirurgenvereinigung e.V., 15. Januar 2014, Saarbrücken, Deutschland. [Oral]

     

    2013

    • Kiemer A.K. (2013). Inflammatory activation of cells from the cardiopulmonary system by oxidic nanoparticles. Nanosafety 2013, 22.-23. Nov 2013, INM, Saarbruecken, Germany. [Oral]

    • Peuschel H., C. Cavelius, and A. Kraegeloh (2013). Uptake and intracellular distribution of core-shell iron oxide particles in Caco-2 cells. Nanosafety 2013, 22.-23. Nov 2013, INM, Saarbruecken, Germany. [Poster]

    • Kraegeloh A. , C. Cavelius, H. Peuschel, K. Boese, and M. Kucki (2013). Nanoparticle interactions on a cellular scale. Carbon Black Symposium, 24.-25. October 2013, Forschungszentrum Borstel, Borstel, Germany. [Oral]

    • Kraegeloh A. (2013). NanoKon – Systematische Bewertung der Gesundheitsauswirkungen nanoskaliger Kontrastmittel. NanoMed Workshop, 12. June 2013, Friedrich-Schiller-Universitaet, Jena, Germany. [Oral]

    • Senger S., S.G. Mueller, M.W. Laschke, and M.D. Menger (2013). Leukocyte-endothelial cell interaction in brain vessels is enhanced by circulating silver nanoparticles .Jahrestagung der DGNC, 26.-29. May 2013, Germany. [Poster]

    • Kucki M., C. Cavelius, and A. Kraegeloh (2013). Nanoscale contrast agents – Particle uptake, subcellular distribution and morphological effects. BioNanoMed 2013, 4th International Congress Nanotechnology, Medicine & Biology, 13.-15. March 2013, Krems, Austria. [Poster]

    • Kucki M. (2013). NanoKon – Systematische Bewertung der Gesundheitsauswirkungen nanoskaliger Kontrastmittel. 3. Clustertreffen der BMBF-Foerdermaßnahmen NanoCare und NanoNature, DECHEMA, 14.-15. January 2013, Frankfurt/Main, Germany. [Oral]

    • Astanina K., Kiemer A.K. (2013). Iron oxide nanoparticles: intracellular transport and localization. 3. Clustertreffen der BMBF-Foerdermaßnahmen NanoCare und NanoNature, DECHEMA, 14.-15. January 2013, Frankfurt/Main, Germany. [Poster]

    • Mueller A., S. Mueller,T. Jung, A. Kraegeloh, C. Cavelius, M. Laschke (2013). Untersuchung der bildgebenden Eigenschaften neuartiger Gd-haltiger Nanopartikel in der Magnetresonanztomographie. 3. Clustertreffen der BMBF-Foerdermaßnahmen NanoCare und NanoNature, DECHEMA, 14.-15. January 2013, Frankfurt/Main, Germany. [Poster]

    • Mueller S., A. Mueller, T. Jung, A. Kraegeloh, C. Cavelius, and M. Laschke (2013). In-vitro-Charakterisierung neuartiger Gd-haltiger Nanopartikel auf BaSO4-Basis. 3. Clustertreffen der BMBF-Foerdermaßnahmen NanoCare und NanoNature, DECHEMA, 14.-15. January 2013, Frankfurt/Main, Germany. [Poster]

    • Kucki M., C. Cavelius, and A. Kraegeloh (2013). Nanoscale Contrast Agents: Microscopical Analysis of Particle Uptake and Intracellular Localisation. 3. Clustertreffen der BMBF-Foerdermaßnahmen NanoCare und NanoNature, DECHEMA, 14.-15. January 2013, Frankfurt/Main, Germany. [Poster]

    • Jung T., C. Cavelius, H. Schirra, D. Kreischer, A. Kurz, A. Schwarz, A. Kraegeloh, and R. Danzebrink (2013). Nanoscale Contrast Agents: Synthesis, Modification and Characterization. 3. Clustertreffen der BMBF-Foerdermaßnahmen NanoCare und NanoNature, DECHEMA, 14.-15. January 2013, Frankfurt/Main, Germany. [Poster]

    • Docter D., N. Habtemichael, S. Tenzer, V. Fetz, D. Goeßwein, A. Hahlbrock, and R. H. Stauber (2013). The Dynamic Nanoparticle-Protein Corona - Implications for Nano-Toxicology and – Biomedicine. 3. Clustertreffen der BMBF-Foerdermaßnahmen NanoCare und NanoNature, DECHEMA, 14.-15. January 2013, Frankfurt/Main, Germany. [Poster]

     

    2012

    • Kucki M., C. Cavelius, and A. Kraegeloh (2012). The devil is in the details – Endotoxin-Detection in Nanoparticle Formulations. SENN – International Congress on Safety of Engineered Nanoparticles and Nanotechnologies, 28.-31. October 2012, Helsinki, Finnland. [Poster]

    • Docter D., V. Fetz, W. Mann, and R. H. Stauber (2012). Proteomic Profiling of the Dynamic Nanoparticle-Plasma Protein Corona - Implications for Biomedical Applications. The 6th International Conference on Nanotoxicology 2012, Beijing, VR China. [Poster]

    • Kraegeloh A. (2012). NanoKon – novel nanoscaled contrast agents and systematic evaluation of their safety. NanoMed Workshop, 26.-27. June 2012, Friedrich-Schiller-Universitaet, Jena, Germany. [Oral]

    • Kucki M., C. Cavelius, S. Schmidt, and A. Kraegeloh (2012). Nanoskalige Kontrastmittel: Endotoxin-Bestimmung und mikroskopische Darstellung. 2. Clustertreffen der BMBF-Foerdermaßnahmen NanoCare und NanoNature, DECHEMA, 13 – 14. March 2012, Frankfurt/Main, Germany. [Poster]

    • Kraegeloh A. (2012). NanoKon –systematische Bewertung der Gesundheitsauswirkungen nanoskaliger Kontrastmittel. 2. Clustertreffen der BMBF-Foerdermaßnahmen NanoCare und NanoNature, DECHEMA, 13 – 14. March 2012, Frankfurt/Mayn, Germany. [Oral]

    • Jung T., C. Cavelius, H. Schirra, D. Kreischer, A. Kurz, S. Schmidt, A. Kraegeloh, and R. Danzebrink (2012). Synthese und Charakterisierung nanoskaliger FexOy und BaSO4 Suspensionen als MRT / CT Kontrastmittel. 2. Clustertreffen der BMBF-Foerdermaßnahmen NanoCare und NanoNature, DECHEMA, 13 – 14. March 2012, Frankfurt/Main, Germany. [Poster]

    • Docter D., N. Habtemichael, S. Tenzer, and R. H. Stauber (2012). Proteomic Profiling of the Nanoparticle/Protein Corona. 2. Clustertreffen der BMBF-Foerdermaßnahmen NanoCare und NanoNature, DECHEMA, 13 – 14. March 2012, Frankfurt/Main, Germany. [Poster]

    • Zarbock R., J. Hoppstaedter, B. Diesel, B. Wahl, A. Kraegeloh, and A.K. Kiemer (2012). Macrophage Models. BioBarriers 2012, 9th International Conference and Workshop on Biological Barriers, 29.02.-09.03.2012, Saarland University, Saarbruecken, Germany. [Oral]

    • Kucki M., C. Cavelius, A. R. Jochem, S. Schmidt, and A. Kraegeloh (2012). Interference of Nanoparticle Suspensions with the recombinant Factor C Endotoxin-Detection System. BioBarriers 2012 - 9th International Conference and Workshop on Biological Barriers, 29.02.-09.03.2012, Saarland University, Saarbruecken, Germany. [Poster]

    • Kucki M., C. Cavelius, and A. Kraegeloh (2012). Hide and Seek – Endotoxin-Detection in Nanoparticle Suspensions. NanoImpactNet – QNano Konferenz „From theory to practice – development, training and enabling nanosafety and health research", 27.-29. February 2012, Dublin, Ireland. [Poster]

     

    2011

    • Senger S., S.G. Mueller, M.W. Laschke, and M.D. Menger (2011). Leukocyte-endothelial cell interaction in brain vessels is enhanced by circulating silver nanoparticles. Joint Meeting der 'European Society of Microcirculation (ESM)‚ und der 'German Society of Microcirculation und Vascular Biology (GfMVB)', 13.-16. October 2011, Muenchen, Germany. [Poster]

    • Mueller S.G., S. Senger, M.W. Laschke and M.D. Menger (2011). In vivo analysis of nanoparticle-endothelial cell interaction in a colitis mouse model. Joint Meeting der 'European Society of Microcirculation (ESM)‚ und der 'German Society of Microcirculation und Vascular Biology (GfMVB)', 13.-16. October 2011, Muenchen, Germany. [Poster]

    • Mueller S.G., S.Senger, M.W.Laschke, and M.D.Menger (2011). In vivo Analyse der Nanopartikel Endothelzell-Interaktion in einem Kolitis-Modell der Maus. 15. Chirurgische Forschungstage 2011, Medizinisch Theoretisches Zentrum (MTZ) der Technischen Universitaet Dresden, 22 – 24 September 2011, Dresden, Germany. [Poster]

    • Senger S., S.G.Mueller, M.W.Laschke, and M.D.Menger (2012). Zirkulierende Silber-Nanopartikel verstaerken die Leukozyten Endothelzell-Interaktion an der Blut-Hirn-Schranke. 15. Chirurgische Forschungstage 2011, Medizinisch Theoretisches Zentrum (MTZ) der Technischen Universitaet Dresden, 22 – 24 September 2011, Dresden, Germany. [Poster]

    • Mueller A., G. Schneider, S. Mueller, M. Laschke, and A. Buecker (2011). Magnetresonanztomographische Charakterisierung des Referenzpartikels USPIO. 1. Clustertreffen zu den BMBF-Foerdermaßnahmen NanoCare und NanoNature, 10.-11. May 2011, DECHEMA, Frankfurt/Main, Germany. [Poster]

    • Mueller S.G., M.W. Laschke, and M.D. Menger (2011). In vivo Analyse der Aufnahme, Verteilung und Toxizitaet nanoskaliger Kontrastmittel. 1. Clustertreffen zu den BMBF-Foerdermaßnahmen NanoCare und NanoNature, 10.-11. May 2011, DECHEMA, Frankfurt/Main, Germany. [Poster]

    • Kucki M., C. Cavelius, S. Schmidt, and A. Kraegeloh (2011). Referenzmaterial Eisenoxid-Nanopartikel: Fluoreszenzmarkierung, Endotoxingehalt und Verhalten in zellbasierten Assays. 1. Clustertreffen zu den BMBF-Foerdermaßnahmen NanoCare und NanoNature, 10.-11. May 2011, DECHEMA, Frankfurt/Main, Germany. [Poster]

    • Kraegeloh A. (2011). Vorstellung des NanoKon-Projektes. 1. Clustertreffen zu den BMBF-Foerdermaßnahmen NanoCare und NanoNature, 10.-11. May 2011, DECHEMA, Frankfurt/Main, Germany. [Oral]

    • Jung T., C. Cavelius, H. Schirra, A. Kurz, S. Schmidt, A. Kraegeloh, R. Hanselmann, and R. Danzebrink (2011). Physikochemische Charakterisierung der Referenzmaterialien. 1. Clustertreffen zu den BMBF-Foerdermaßnahmen NanoCare und NanoNature, 10.-11. May 2011, DECHEMA, Frankfurt/Main, Germany. [Poster]

    • Docter D., V. Fetz, C. Bier, and R. H. Stauber (2011). In vitro-Analyse biologischer Auswirkungen nanoskaliger Kontrastmittel auf den Magen-Darmtrakt (BioProfile). 1. Clustertreffen zu den BMBF-Foerdermaßnahmen NanoCare und NanoNature, 10.-11. May 2011, DECHEMA, Frankfurt/Main, Germany. [Poster]

    • Astanina K., S. Petry, and A.K. Kiemer (2011). Interaction of human endothelial cells with iron oxide nanoparticles (ENDOREM®). 1. Clustertreffen zu den BMBF-Foerdermaßnahmen NanoCare und NanoNature, 10.-11. May 2011, DECHEMA, Frankfurt/Main, Germany. [Poster]

     

    2010

    • Kraegeloh A., C. Brochhausen, R. Danzebrink, A.K. Kiemer, M.W. Laschke, L. Santen, G. Schneider, R. Stauber, and R. Hanselmann (2010). NanoKon – novel nanoscaled contrast agents and systematic evaluation of their safety. NanoMed 2010 – 7th International Conference on Biomedical Applications of Nanotechnology, 2.-3. December 2010, Berlin, Germany. [Poster]

     
    Final Scientific Reports (in German only)

    Final Scientific Reports (in German only)

    NanoKon Konsortium (2014). NanoKon - Systematische Bewertung der Gesundheitsauswirkungen nanoskaliger Kontrastmittel : Berichtszeitraum: 01.10.2010 - 31.12.2013; Abschlussbericht; Annette Kraegeloh et al., INM - Leibniz-Institut für Neue Materialien gGmbH, FKZ 03X0100A-E, TIB Hannover.

     

     
    Patents

    Patents

    • Kraegeloh, A; Kucki, M. "Verfahren zur Detektion von Endotoxinen und/oder 1,3-beta-D-Glucanen in einer Probe", DE 102012110288 A1, 26.10.2012 (Prioritätsdatum).

     

     

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